Thalamic neuroplasticity and pain following spinal cord injury

疼痛是脊髓损伤患者的主要问题，也是常见、严重和难以治疗的问题。越来越多的证据表明，疼痛可能与脊髓损伤后某些脑区的特定变化有关。一些可能的脑部变化已经被提出，但还没有得到充分的研究，对治疗有不同的影响。该项目旨在描述这些大脑变化的特征，目的是开发新的、有效的和有针对性的治疗方法。

Pain is a major problem for people with spinal cord injuries and is common, severe and difficult to treat. There is increasing evidence to suggest that pain may be linked to specific changes in some brain regions following a spinal cord injury. Several possible brain changes have been suggested but not investigated fully and have different implications for treatment. This project aims to characterise these brain changes with the purpose of developing novel effective and targeted treatments.