Trial to Evaluate Anti-fibrinolytic Therapy in Thrombocytopenia (TREATT)

恶性血液病患者由于自身疾病或治疗导致血小板计数低。这可能与出血有关，有时可能是严重的或致命的。在澳大利亚，近三分之二的血小板输注是在这种情况下进行的，目的是防止出血，但许多人仍然会出血。本研究询问氨甲环酸是否可以安全有效地减少出血，如果可以，减少出血是否导致血小板输注减少？

Patients with haematologic malignancies often have low platelet counts from their disease or treatment. This can be associated with bleeding, which can sometimes be serious or fatal. Nearly 2/3 of all platelet transfusions in Australia are given in this setting to try to prevent bleeding but many people still experience bleeding. This study asks whether tranexamic acid can safely & effectively reduce bleeding and if it does, does reduced bleeding lead to reduction in platelet transfusions?