Understanding the role of treatment timing cells and human genetics to explain why HIV drugs do not cure HIV.
Understanding the role of treatment timing cells and human genetics to explain why HIV drugs do not cure HIV.
批准号:
nhmrc : GNT1061681
负责人:
A/Pr Paul Cameron
金额:
$87.34万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 --
中文摘要
这项与临床相关的研究由全球知名的艾滋病毒科学家和医生团队进行,对新兴的艾滋病毒根除和治疗领域做出了重大贡献。这项研究获取了来自艾滋病毒患者的多样化和独特的样本集,并应用了创新的、超敏感的基因测量技术,最终确定了体内存有持久性艾滋病毒的宿主,以便他们能够成为新疗法的靶子,这是旨在根除艾滋病毒的努力的关键一步。
英文摘要
Conducted by a globally-renown team of HIV scientists and physicians, this clinically-relevant study makes a significant contribution to the emerging field of HIV eradication and cure. Accessing diverse and unique sample sets from HIV patients and applying innovative, ultra-sensitive genetic measurement techniques, the study definitively identifies the bodily reservoirs harbouring persistent HIV so they can be targeted by new therapies, a crucial step for efforts aimed at HIV eradication.
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会议论文
RNA processing mechanisms controlling HIV latency
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批准号:nhmrc : 1129320
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项目类别:Project Grants
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资助金额:$41.28万
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财政年份:2017
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负责人:A/Pr Paul Cameron
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依托单位:
RNA processing mechanisms controlling HIV latency
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批准号:nhmrc : GNT1129320
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项目类别:Project Grants
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资助金额:$60.51万
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财政年份:2017
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负责人:A/Pr Paul Cameron
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依托单位:
Long term persistence of HIV in the liver and the clinical impact on HIV-HBV co-infection
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批准号:nhmrc : GNT1101836
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项目类别:Project Grants
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资助金额:$139.32万
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财政年份:2016
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负责人:A/Pr Paul Cameron
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依托单位:
Long term persistence of HIV in the liver and the clinical impact on HIV-HBV co-infection
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批准号:nhmrc : 1101836
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项目类别:Project Grants
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资助金额:$95.94万
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财政年份:2016
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负责人:A/Pr Paul Cameron
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依托单位:
The impact of HIV integration sites on eliminating HIV latency
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批准号:nhmrc : 1058891
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项目类别:Project Grants
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资助金额:$51.9万
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财政年份:2014
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负责人:A/Pr Paul Cameron
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依托单位:
Characterising latent HIV reservoirs: examining the effects of treatment initiation, cellular type and patient genetics.
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批准号:nhmrc : 1061681
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项目类别:Project Grants
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资助金额:$60.64万
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财政年份:2014
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负责人:A/Pr Paul Cameron
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依托单位:
HIV latency and regulation of HIV life cycle.
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批准号:nhmrc : 1041795
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项目类别:Project Grants
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资助金额:$33.84万
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财政年份:2013
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负责人:A/Pr Paul Cameron
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依托单位:
Dendritic cell modulation of HIV-1 immunity during DNA vaccination
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批准号:nhmrc : 991132
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项目类别:NHMRC Strategic Awards
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资助金额:$12.44万
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财政年份:1999
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负责人:A/Pr Paul Cameron
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依托单位:
HIV-1 selection by dendritic cells in human blood and skin explants
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批准号:nhmrc : 991482
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项目类别:NHMRC Strategic Awards
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资助金额:$12.11万
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财政年份:1999
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负责人:A/Pr Paul Cameron
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依托单位:
Evasion of antiviral immunity by latent and productive HIV-1 infection in dendritic cells and macrophages
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批准号:nhmrc : 991133
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项目类别:NHMRC Strategic Awards
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资助金额:$13.17万
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财政年份:1999
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负责人:A/Pr Paul Cameron
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依托单位:
国内基金
海外基金
PfAP2-R介导的PfCRT转录调控在恶性疟原虫对喹啉类药物抗性中的作用及机制研究
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批准号:82372275
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:刘耀宝
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依托单位:
Sestrin2抑制内质网应激对早产儿视网膜病变的调控作用及其机制研究
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批准号:82371070
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:赵培泉
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依托单位: