Using modelling to evaluate STI epidemiology control strategies and investigate chlamydial within-host disease

这项研究将进一步加深我们对细胞内衣原体发展机制的理解，以及它如何导致疾病，最终为药物疫苗设计提供目标。该项目还将设计和评价流行病控制战略，以便决策者了解如何减少性传播感染的发病率和流行率。这些应用是通过开发数学模型，生物物理理论和统计分析来解决的。

This research will further our understanding of the mechanisms that give rise to the development of Chlamydia within a cell and how it causes disease, ultimately providing targets for drug-vaccine design. This project will also design and evaluate epidemic control strategies to inform policy makers for reducing the incidence and prevalence of sexually transmitted infections. These applications are addressed by developing mathematical models, biophysical theory, and statistical analyses.