Development and characterisation of novel hydrogel systems for drug delivery

新型药物递送水凝胶系统的开发和表征。该项目的目的是开发和表征用于递送活性剂（如蛋白质药物）的水凝胶配方，并检查对载药水凝胶的生物反应。在许多医疗和工业领域，控制活性剂的释放是有利的。控制释放可以减少必须施用的活性剂量，维持环境中制剂的更恒定水平，并可以将制剂定位在需要的部位。该项目将推进聚合物降解与蛋白质释放结合的理论知识，将开发可应用于医疗设备的可控释放水凝胶技术，并将培养生物材料和药物输送方面的研究生。

Development and characterisation of novel hydrogel systems for drug delivery. The aims of this project are to develop and characterise hydrogel formulations for delivery of active agents, such as protein drugs, and to examine the biological responses to drug loaded hydrogels. In many medical and industrial fields, it is advantageous to control the release of active agents. Controlled release can decrease the dose of active that must be administered, sustain a more constant level of the agent in the environment and can localise the agent at the site where it is needed. This project will advance the theoretical knowledge of polymer degradation combined with protein release, will develop controlled release hydrogel technology that can be applied to medical devices and will train a postgraduate student in biomaterials and drug delivery.