Nanoporous Molecular Frameworks: Chirality, Host-Guest Chemistry and Nanoscale Templation

纳米多孔分子框架：手性，主-客体化学和纳米尺度模板。分子骨架材料是一类新型的纳米多孔材料，由于其可逆的、选择性的客体交换以及其巨大的结构和化学通用性，有望获得广泛的应用。该项目涉及该领域的三个重点：1）使用纯手性（手）框架进行分子对映体分离，2）这些系统中的客体交换机制，以及3）使用这些材料作为多孔模板，在其中可以生长其他纳米结构材料。除了具有相当大的基本利益外，这项工作还有望在药物纯化和纳米材料领域带来许多重大的商业利益。

Nanoporous Molecular Frameworks: Chirality, Host-Guest Chemistry and Nanoscale Templation. Molecular frameworks are a new class of nanoporous material that promise a range of applications due to their reversible, selective guest-exchange and their great structural and chemical versatility. This project addresses three points of focus within this area: 1) the use of homochiral (handed) frameworks for molecular enantioseparations, 2) the mechanisms of guest-exchange in these systems, and 3) the use of these materials as porous templates within which other nanostructured materials may be grown. In addition to having considerable fundamental interest, the work promises a number of significant commercial benefits in the areas of drug purification and nanomaterials.