Pathogenesis, regulation and genomics of the ovine footrot pathogen, Dichelobacter nodosus

羊足病致病菌结节双杆菌的发病机制、调控及基因组学研究。在澳大利亚，羊蹄病是最具经济意义的疾病之一。该项目的目的是详细了解引起这种感染的细菌如何能够感染羊蹄并导致临床疾病。致病细菌基因组的完整序列将被确定，使我们能够推断其遗传潜力。完成的项目将大大提高对疾病过程的基础知识，并将导致疾病控制的改进方法的发展，同时为澳大利亚的第一产业节省成本。

Pathogenesis, regulation and genomics of the ovine footrot pathogen, Dichelobacter nodosus. Footrot is one of the most economically significant diseases of sheep in Australia. The aim of this project is to develop a detailed understanding of how the bacterium that causes this infection is able to infect the sheep hoof and result in clinical disease. The complete sequence of the genome of the causative bacterium will be determined, enabling us to deduce its genetic potential. The completed project will significantly advance fundamental knowledge of the disease process and will lead to the development of improved methods for the control of the disease, with concomitant cost savings to Australian primary industry.