The first stage of vision: transduction and adaptation in retinal photoreceptors
The first stage of vision: transduction and adaptation in retinal photoreceptors
批准号:
ARC : FF0344672
负责人:
金额:
$141.75万
依托单位国家:
澳大利亚
项目类别:
Federation Fellowships
财政年份:
2003
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2003-01-01 至 2007-12-31
中文摘要
视觉的第一阶段:视网膜光感受器的转导和适应。该项目旨在提供对视觉第一阶段所涉及的分子步骤的详细了解-在视网膜的视杆和视锥感光细胞中将光转换为神经信号。它的意义在于,它将解释使我们能够看到的最初事件,并将有助于解释当这一过程失败时发生的赤字。其结果将是全面了解我们的光感受器如何以极高的灵敏度、极快的速度以及在巨大的光强度范围内做出反应,从而赋予我们非凡的视觉感觉。
英文摘要
The first stage of vision: transduction and adaptation in retinal photoreceptors. The project aims to provide a detailed understanding of the molecular steps involved in the first stage of vision - the conversion of light into a neural signal in the rod and cone photoreceptors of the retina. The significance of this is that it will explain the initial events that enable us to see, and will help explain the deficits that occur when the process fails. The outcome will be a comprehensive understanding of how our photoreceptors respond with extreme sensitivity, yet great rapidity, and over an enormous range of light intensities, thus endowing us with our remarkable sense of vision.
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