Advanced mathematical modelling and numerical simulation of blood flow: from the microscale to the macroscale

在提议的项目中，我们的目标是在过去五年中我们在血液流变学领域的研究成果的基础上，提供从大直径血管（宏观尺度，连续体或微观宏观描述）到微血管（微观尺度，离散建模方法）的体外血液流动的详细流变描述。我们的目标是能够使用任何一种方法一致地描述中等大小（直径约100微米）的血管中的流动。只要有可能，我们将继续致力于对我们的定量预测进行实验验证。

In the proposed project we aim to build on our research achievements in the area of haemorheology over the past five years to provide a detailed rheological description of in vitro blood flows all the way from those in large diameter vessels (macroscale, continuum or micro-macro description) to those in the microvasculature (microscale, discrete modelling methods). We aim to be able to consistently describe flows in vessels of intermediate size (c. 100 microns in diameter) using either approach. We will continue our commitment to the experimental validation, wherever possible, of our quantitative predictions.