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The physiological roles of PAPPA2

The physiological roles of PAPPA2
PAPPA2的生理作用
批准号:
326791-2011
负责人:
Christians, Julian
金额:
$2.26万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31

项目摘要

项目成果

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中文摘要
翻译
我的研究目标是了解物种内连续性状(如体型)变异的生理和遗传因素。在之前的工作中,我确定了PAPPA2基因在控制小鼠生长变异方面具有潜在的重要作用。人们对PAPPA2知之甚少,但与PAPPA结构相关的基因PAPPA在妊娠、骨骼发育、心血管疾病、皮肤愈合和衰老等多种过程中都很重要。
英文摘要
The goal of my research is to understand the physiological and genetic factors underlying within-species variation in continuous traits such as body size. In previous work, I identified the PAPPA2 gene as potentially important for controlling variation in growth in mice. Little is known about PAPPA2, but a structurally related gene, PAPPA, is important in a variety of processes including pregnancy, bone development, cardiovascular disease, skin healing and aging.
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  • 资助金额:
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  • 财政年份:
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Sex-dependent fetal and placental responses to adversity
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    RGPAS-2021-00009
  • 项目类别:
    Discovery Grants Program - Accelerator Supplements
  • 资助金额:
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  • 批准号:
    RGPIN-2021-02853
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
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