The Role of ADAM17 in the Pathogenesis of Diabetic Nephropathy
The Role of ADAM17 in the Pathogenesis of Diabetic Nephropathy
批准号:
237912
负责人:
Krepinsky Joan
金额:
$41.47万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2016-09-01
中文摘要
糖尿病是肾衰竭最常见的原因。在糖尿病肾脏中,瘢痕蛋白(基质)积聚在过滤单位(肾小球)中并阻止它们正常运作。目前尚不清楚高葡萄糖水平如何导致肾小球(MES
英文摘要
Diabetes is the most common cause of kidney failure. In the diabetic kidney, scar proteins (matrix) accumulate in the filtering units (glomeruli) and prevent them from functioning properly. It is not yet known how high glucose levels cause glomerulus (mes
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