The role of longin-SNAREs in proteins sorting and membrane fusion

胞吐和膜融合是所有细胞维持其生存和执行其独特功能的机制。这一过程包括将细胞内的囊泡运输到细胞外围，在那里它们停靠并经历膜融合，导致它们的内容物在细胞外释放。例如，白细胞可以通过释放细胞内酶和炎症的化学介质来攻击和降解入侵的病原体。由于这些酶和化学物质是有毒的，它们被隔离在被称为囊泡的细胞内包装中，只有当感觉到入侵的病原体时，它们才会在细胞外围通过胞吐和膜融合释放出来。

Exocytosis and membrane fusion are mechanisms used by all cells to maintain their survival and perform their unique functions. This process involves the transport of intracellular vesicles to the cell periphery where they dock and undergo membrane fusion, resulting in the release of their contents extracellularly. For example, white blood cells can attack and degrade invading pathogens by releasing intracellular enzymes and chemical mediators of inflammation. Since these enzymes and chemicals are toxic they are sequestered in intracellular packages called vesicles and only released by exocytosis and membrane fusion at the cell periphery when invading pathogens are sensed.