Novel Influenza Neuraminidase Inhibitors - Development of Orally Bioavailable Agents

流感神经氨酸酶（也称为唾液酸酶）是临床验证的控制流感感染的酶靶点。在四种被批准的抑制这种酶的药物中，只有达菲（奥司他韦）是口服的，因此占主导地位

Influenza neuraminidase (also known as a sialidase) is a clinically validated enzyme target for control of influenza infections. Of the four approved drugs that inhibit this enzyme, only Tamiflu (oseltamivir) is orally available, and thus dominates the ne