A Sonicator for Optimal DNA Shearing for Next-Generation Sequencing Library Preparation

我们研究计划的目标是更好地了解植物对广谱病原体的免疫系统。对植物抵抗病原体感染能力的进一步了解将使我们能够设计可持续和环境友好的方法来减轻植物疾病造成的作物歉收。在过去的几年中，我们的团队在确定转录调控，核质运输，蛋白质修饰和RNA加工在植物免疫中的重要作用方面取得了开创性的发现。我们已经发现了许多对植物抵抗病原体至关重要的新型调节剂。未来的努力将确定植物免疫中缺失的参与者，并阐明所有这些组成部分如何共同发挥作用以产生防御反应。我们研究项目的成功在很大程度上依赖于我们学习和使用最新开发技术的能力，例如下一代测序。

The goal of our research program is to better understand the immune system of plants against a broad spectrum of pathogens. An improved understanding of plants' ability to fight against pathogen infections will enable us to design sustainable and environmentally friendly ways to alleviate crop failure caused by plant diseases. During the past few years, our group has made pioneering discoveries in determining the essential roles of transcriptional regulation, nucleocytoplasmic trafficking, protein modification, and RNA processing in plant immunity. We have discovered a number of novel regulators critical for plant resistance against pathogens. Future efforts will be made to identify the missing players in plant immunity and elucidate how all these components function together to mount a defense response. The success of our research program relies heavily on our capability to learn and use recently developed technologies, such as next-generation sequencing.