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Mechanisms of motor unit protection by exercise training in aging muscle

Mechanisms of motor unit protection by exercise training in aging muscle
运动训练对衰老肌肉的运动单位保护机制
批准号：
265559
负责人：
Hepple Russell T
金额：
$43.85万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-09-01 至 2017-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=265559&lang=en
关键词：
Aging Denervation Endurance Exercise Training Immunofluorescence Microscopy Mitochondrial Function Motor Unit Neuromuscular Junction Sarcopenia Transcriptome

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中文摘要
翻译
定期的耐力运动训练可以减缓与年龄相关的肌肉质量和功能的损失，称为肌肉减少症。尽管有充分的证据表明这是事实，但这种情况发生的细胞机制在很大程度上是未知的。拟议的实验侧重于
英文摘要
Regular endurance exercise training slows the age-related loss of muscle mass and function known as sarcopenia. Despite ample evidence this is the case, the cellular mechanisms by which this occurs are largely unknown. The proposed experiments focus upon
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会议论文
Skeletal Muscle Dysfunction in Critical Care Medicine
Relationship between denervation, mitochondrial dysfunction, and muscle atrophy in sarcopenia
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