Separate and combined effects of temperature and oxygen on neuromuscular function

在过去的十年里，高体温已经被认为是导致自主运动能力和耐力下降的直接原因。然而，体温影响运动能力的机制仍然是争论的主要来源。其中一个研究领域关注的是温度对肌肉的影响。较高的体温似乎会直接降低大脑招募和激活肌肉的能力。然而，较高的肌肉温度本身或较高的皮肤温度也会降低对运动的耐受性。因此，研究这些不同的温度输入如何共同影响肌肉功能是很重要的。同时，温度的变化也会影响大脑和肌肉的血流量和氧气输送量，而大脑或肌肉可获得的氧气对实际的肌肉功能有很大的影响。因此，为了了解温度对肌肉功能的实际影响，研究哪些是由氧气变化引起的，哪些是由温度引起的变得很重要。这是本研究的主要目的。

Over the past decade, a high body temperature has become recognized as a direct cause of decreased voluntary exercise capacity and tolerance. However, the mechanism by which body temperature influences exercise capacity remains a major source of debate. One area of research has focused on the effects of temperature on our muscles. Higher body temperature appears to directly reduce the brain's ability to recruit and activate muscles. However, higher muscle temperature by itself or a higher skin temperature can also reduce tolerance to exercise. Therefore, it is important to study how these different temperature inputs combine to affect muscle function. At the same time, temperature changes also affect the amount of blood flow and oxygen delivery to the brain and muscles, and the oxygen available to the brain or muscles is a powerful influence on actual muscle function. Thus, in order to understand the actual effects of temperature on muscle function, it becomes important to study what is due to oxygen changes and what is due to temperature. This is the main goal of the proposed research.