Multibody dynamic modeling of the upper limb for the quantification of muscle force co-contraction and synergy strategies during motion

这个生物医学工程研究项目的目标是量化健康成年人上肢运动过程中的个体肌力。这也将能够解释肌肉协同收缩策略的时间演变，即关节两侧肌肉的相反动作，以及协同作用，即关节同一侧肌肉的联合动作，用于基础知识和未来在体育、机器人、康复、骨科、人体工效学和/或预防方面的创新应用。该计划包括3个具体目标：1.开发生物逼真和个性化的上肢动态模型，能够量化运动过程中的肌力。2.尽可能使用神经运动阻滞剂进行验证，即局部麻醉选定的肌肉。3.用它来理解在前屈/后伸、旋前/旋后和指点任务中的肌肉过度驱动策略。

The goal of this biomedical engineering research program is to quantify individual muscle forces during upper limb motion in healthy adults. This will also enable to explain the temporal evolution of muscle strategies of co-contraction, i.e. opposite actions of muscles on each side of a joint, and synergy, i.e. joint actions of muscles on the same side of a joint, for fundamental knowledge and future innovative applications in sports, robotics, rehabilitation, orthopedics, ergonomics and/or prevention. The program includes 3 specific objectives: 1. Develop a biofidelic and personalized dynamic model of the upper limb, enabling to quantify muscle forces during motion. 2. Validate it as far as possible using nerve motor blocs, i.e. locally anesthetizing selected muscles. 3. Use it to understand the muscle overactuation strategies during flexion/extension, pronation/supination, and pointing task.