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Cryo-electron Microscopic Analysis of the Structural Basis for the Regulation of Human Epidermal Growth Factor Receptor (EGFR) by Lipids

Cryo-electron Microscopic Analysis of the Structural Basis for the Regulation of Human Epidermal Growth Factor Receptor (EGFR) by Lipids
冷冻电子显微镜分析脂质调节人表皮生长因子受体（EGFR）的结构基础
批准号：
281179
负责人：
Kim Kelly
金额：
$10.93万
依托单位：
Harvard Medical School (Boston, Massachusetts)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-02-01 至 2016-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=281179&lang=en
关键词：
Cancer Cell Signalling Cryo-Electron Microscopy Epidermal Growth Factor Receptor Lipid Membrane Protein Nanodisc Protein Expression Protein Purification

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翻译
膜蛋白负责许多基本的细胞过程，它们的功能障碍经常导致疾病，包括许多类型的癌症。因此，膜蛋白在生物医学上引起了极大的兴趣，但实现了其作为药物的潜力
英文摘要
Membrane proteins are responsible for many essential cellular processes and their dysfunction often results in diseases, including many types of cancer. Membrane proteins are therefore of great biomedical interest, but realizing their potential as drug ta
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