Assisting workflow in biomanufacturing with data visualizations
Assisting workflow in biomanufacturing with data visualizations
批准号:
470152-2014
负责人:
Burns, Catherine
金额:
$1.82万
依托单位:
依托单位国家:
加拿大
项目类别:
Engage Grants Program
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31
中文摘要
据估计,每个工厂每60周就会发生一次生物技术生产中的批次故障。一批活性成分如果丢失,仅销售收入损失就相当于1 500万美元。生物技术制造中的操作员需要易于在心理上处理的实时分析,以有效管理批处理。车间使用的传统技术并不能帮助操作员防止警报状态下的批次故障。此外,从批量生产经验中获得的知识对公司来说是丢失的,并且需要通过提供趋势分析的解决方案来确定最佳实践结果。该项目将分析生物技术制造工厂的工作流程,从操作人员那里获得技术要求,并相应地提供原型解决方案。将确定导致批次失效的生产工艺中的关键参数,
英文摘要
It is estimated that batch failures in biotechnology manufacturing occur every 60 weeks per facility. A single batch of an active ingredient if lost would equate to a sales revenue loss of $15 million alone. Operators in biotechnology manufacturing require real-time analytics that are easy to mentally process for effective management of batch processing. Conventional technologies used on the shop floor are not designed to help operators prevent failures of batches in alarm condition. Moreover, knowledge gained from batch production experiences are lost to the corporation and there is a need to identify best-practice results with solutions that provide trending analytics. This project will analyze the workflow in a biotechnology manufacturing plant, elicit technology requirements from operators, and accordingly deliver a prototype solution. Critical parameters in the manufacturing process underlying batch failures will be identified and analytical solutions will be
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依托单位:
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海外基金