Aptamer-based electrochemical sensor for rapid and quantitative detection of melamine

开发便携、经济有效的定量分析工具来检测三聚氰胺具有重要的现实意义，三聚氰胺是一种源于三聚氰胺树脂工业生产和杀虫剂氯胺嘧啶降解的迫切环境污染物。它还被非法用于动物饲料和婴儿奶粉中的蛋白质掺假。现有的三聚氰胺检测方法，如液质联用法(LC/MS)和电喷雾电离质谱法(ESI-MS)，往往存在复杂、费时、昂贵等缺点。

It is of practical importance to develop portable, cost-effective and quantitative analytical tools for the detection of melamine, an imperative environmental contaminant that originates from the industrial manufacture of melamine resins and from the degradation of the pesticide cryomazine. It has been also illegally used for protein adulterations in animal feed and in infant milk powder. The existing methods for melamine determination, such as liquid chromatography-mass spectrometry (LC/MS) and electrospray ionization mass spectrometry (ESI-MS), are often complex, time consuming and expensive.