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Remodeling of the tumor microenvironment by CD73: a therapeutic target

Remodeling of the tumor microenvironment by CD73: a therapeutic target
CD73 重塑肿瘤微环境:治疗靶点
批准号:
320073
负责人:
Stagg John
金额:
$21.86万
依托单位国家:
加拿大
项目类别:
Salary Programs
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-12-01 至 2019-12-01
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中文摘要
翻译
CD73是一种在乳腺癌中过度表达的细胞结合酶。最近,我的工作表明CD73在乳腺癌中的表达与肿瘤生长和转移增加有关。此外,我已经证明CD73抑制可以显著
英文摘要
CD73 is a cell-bound enzyme overexpressed in breast cancer. Recently, my work has shown that the expression of CD73 in breast cancer is associated with increased tumor growth and metastasis. Furthermore, I have shown that CD73 inhibition can significantly
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会议论文
Deciphering the role of protease-activated receptor 2 in immuno-oncology
Targeting the extracellular adenosine pathway in pancreatic and liver cancers
Immune-stimulatory antibody-drug conjugates for treatment of breast cancer
  • 批准号:
    388207
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.81万
  • 财政年份:
    2018
  • 负责人:
    Stagg John
  • 依托单位:
Targeting the CD73-adenosine pathway in cancer
海外基金