Using molecular microbiology to improve surgical implants

包膜痉挛是免疫系统对人体内异物的一种反应，是 主要与隆胸的并发症有关。包膜痉挛通常可以是 疼痛，总是需要额外的手术来更换受影响的植入物。据推测， 乳房植入物上的细菌生物膜可能会引起慢性炎症，导致包膜痉挛。这个 行业合作伙伴Nick Carr，Inc.寻求改进预防措施，以抑制术后 通过更好地了解负责细菌的多样性和功能来实现微生物定植， 植入物表面菌落的相互作用。这项研究试图提供一个完整的 囊膜挛缩症相关定植细菌的鉴定及其功能多样性 现代微生物技术。这项研究的信息可以扩展到帮助预防囊膜痉挛 来自其他医疗程序，包括涉及人工关节假体的程序。行业合作伙伴将 利用这些信息来帮助减少加拿大各地囊状肌挛缩的发生和严重程度。

Capsular contracture is an immune system response to foreign materials in the human body and is predominantly associated with complications from breast augmentation. Capsular contracture can often be painful and always requires additional surgery to replace the affected implant. It has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture. The industry partner Nick Carr, Inc. seeks to improve the preventative measures employed to inhibit post-operative microbial colonization through a greater understanding of the diversity and function of the bacteria responsible, and the interaction of the colony at the implant surface. This research seeks to provide a complete identification of the colonizing bacteria associated with capsular contracture and their diverse functions using modern microbial techniques. Information from this study can be expanded to help prevent capsular contracture from other medical procedures, including those involving artificial joint prosthetics. The industry partner will leverage this information to help reduce the occurrence and severity of capsular contracture across Canada.