Immunotherapy against neuroserpin to correct Nerve Growth Factor metabolic dysfunction and consequent cholinergic and cognitive deficits in a transgenic rat model of Alzheimer's disease.
Immunotherapy against neuroserpin to correct Nerve Growth Factor metabolic dysfunction and consequent cholinergic and cognitive deficits in a transgenic rat model of Alzheimer's disease.
批准号:
365444
负责人:
Pentz Rowan D
金额:
$7.65万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2019-10-01
中文摘要
阿尔茨海默病(AD)是我们老龄化人口中日益严重的问题。除非发现新的改善疾病的治疗方法,否则这个问题可能会变得无法控制。
在AD中,基底前脑的胆碱能神经元萎缩或死亡,大多数脑组织中的胆碱能神经元在AD发病后出现萎缩或死亡。
英文摘要
Alzheimer's disease (AD) is an increasing problem in our aging population. Unless new disease-modifying treatments are discovered, the problem may become unmanageable.
In AD, cholinergic neurons of the basal forebrain become atrophic or die, and most brai
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会议论文
Effects of tissue plasminogen activator administration on cholinergic and cognitive deficits in in a transgenic model of Alzheimer's disease-like amyloid pathology
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批准号:311872
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项目类别:Studentship Programs
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资助金额:$1.27万
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财政年份:2013
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负责人:Pentz Rowan D
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依托单位:
海外基金