Microfluidic point-of-care immunoassay

即时检测是在临床实验室之外，在接受治疗的患者附近进行的医学诊断检测，例如在家中、医生办公室和医院的急诊科。在不需要复杂的实验室设备和基础设施的情况下进行诊断测试的能力对许多健康状况（包括癌症、心脏病和病毒感染）都很重要。该提案旨在开发一种新技术，利用为制造硅芯片而开发的方法来执行即时诊断测试，这种方法可以用于精确控制极小体积液体的流动。这种能力使复杂的生化分析可以在便携式、低成本和自动化的系统中进行，可以由患者和护理提供者在护理点使用。

Point-of-care tests are medical diagnostic tests performed outside of clinical laboratories and in close proximity of patients receiving care, such as at homes, doctor's offices, and emergency departments in hospitals. The ability to perform diagnostic tests without requiring sophisticated laboratory equipment and infrastructure is important for many health conditions including cancer, heart disease, and viral infections. This proposal aims to develop a new technology to perform point-of-care diagnostic tests utilizing methods developed for manufacturing silicon microchips, which can be adapted to enable precise control over the flow of extremely small volumes of liquid. This capability enables sophisticated biochemical analyses to be performed in portable, low-cost, and automated system, which can be utilized by patients and care providers at the point of care.