Powering clinical trials research through a secure and integrated data management platform

随着加拿大生活各个领域产生的数据量继续呈指数级增长，需要新的工具以安全可靠的方式合并和分析它们。这一点在生物医学和保健领域可能最为明显，在这两个领域，开放科学的趋势有利于广泛分享数据，而需要维护个人健康信息的隐私和神圣性，两者之间存在着天然的紧张关系。为了充分发挥生物医学大数据在推动医学发现方面的潜力，我们需要新的工具来确保数据可以被最大限度地利用，同时仍然保护加拿大患者的隐私。为了实现这一目标，我们在皇后大学的研究团队将与Indoc Research合作，Indoc Research是一家非营利性公司，致力于建立专注于数据管理和分析的研究基础设施。我们将共同开发FoRCE -专注于研究和临床评估-一个安全共享加拿大重症监护病房患者临床，生理和基因组数据的平台。这些数据为FoRCE的开发提供了最佳用例，但不会是其唯一的应用领域。应用的原则将转化为医疗保健的其他领域，以及其他行业，其中受保护的数据必须在真实的时间共享和分析。FoRCE平台将加速重症监护中以发现为导向的研究，为加拿大和其他地区的重症和受伤患者提供更好的结果。FoRCE还将加强加拿大在信息技术领域的地位，提高加拿大研究和工业在快速增长的数据分析和网络安全领域的地位。

As the quantity of data generated in all sectors of Canadian life continues to grow exponentially, new tools are needed to amalgamate and analyze them in a secure and reliable way. This is perhaps most evident in the fields of biomedicine and health care, where there is a natural tension between trends in open science that favour the widespread sharing of data, and the need to maintain the privacy and sanctity of personal health information. To fully realize the potential of biomedical Big Data to advance discovery in medicine, new tools are needed to ensure that data can be used to the fullest extent possible, while still protecting the privacy of Canadian patients.To achieve this goal, our team of researchers at Queen's University will partner with Indoc Research, a not-for-profit company that builds research infrastructure focused on data management and analytics. Together we will develop FoRCE - Focus on Research and Clinical Evaluation - a platform for the secure sharing of clinical, physiologic, and genomic data from patients in Canada's Intensive Care Units. These data provide an optimal use case for the development of FoRCE, but will not be its only area of application. The principles applied will translate to other areas of health care, as well as other industries, in which protected data must be shared and analyzed in real time.The FoRCE platform will accelerate discovery-oriented research in critical care, delivering improved outcomes for critically ill and injured patients in Canada and beyond. FoRCE will also strengthen Canada's position in the Information Technology sector, raising the profile of Canadian research and industry in the fast-growing world of data analytics and cybersecurity.