Characterizing RecQ helicase Sgs1 in maintaining genomic stability during aging
Characterizing RecQ helicase Sgs1 in maintaining genomic stability during aging
批准号:
369007
负责人:
Cobb Jennifer A
金额:
$71.33万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01
中文摘要
癌症和衰老似乎是截然不同的事情。然而,在衰老和癌症中,我们的细胞对环境挑战的反应能力也发生了类似的变化。例如,对DNA(我们的遗传物质)的损害,会在两个细胞中累积
英文摘要
Cancer and aging are seemingly distinct events. However, similar changes in the ability of our cells to respond to environmental challenges are observed in both aging and cancer. For example, damage to DNA, our hereditary material, accumulates in both ca
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The role of Nej1 in DSB repair pathway choice and MMEJ
-
批准号:433818
-
项目类别:Operating Grants
-
资助金额:$57.19万
-
财政年份:2020
-
负责人:Cobb Jennifer A
-
依托单位:
Characterization of Dyskerin in DNA double-strand break repair
-
批准号:433812
-
项目类别:Operating Grants
-
资助金额:$61.62万
-
财政年份:2020
-
负责人:Cobb Jennifer A
-
依托单位:
3rd Canadian Symposium on Telomeres and Genomic Integrity
-
批准号:334734
-
项目类别:Miscellaneous Programs
-
资助金额:$0.73万
-
财政年份:2015
-
负责人:Cobb Jennifer A
-
依托单位:
Nej1 and Lif1 form structural filaments that bridge the ends of DNA at a DSB
-
批准号:305823
-
项目类别:Operating Grants
-
资助金额:$45.78万
-
财政年份:2014
-
负责人:Cobb Jennifer A
-
依托单位:
Mre11/Rad50/Xrs2 regulates the cohesin complex at sites of replication stress
-
批准号:238885
-
项目类别:Operating Grants
-
资助金额:$54.38万
-
财政年份:2011
-
负责人:Cobb Jennifer A
-
依托单位:
海外基金