Investigation into the roles of Arabidopsis calcium sensors in stress response and development

植物必须不断监测其环境，并以适当的细胞和生理适应来应对变化。当面临不利的环境胁迫，如病原体攻击，干旱或盐度，植物启动特定的，适应性的细胞反应，其中包括基因表达，酶活性和代谢调节的变化。这些反应是通过复杂的信号系统来调节的，这些信号系统有助于将细胞的机制编排成一种协调的反应，这种反应对于给定的压力来说是适当的时间和特定的。植物在对几乎所有类型的生物和非生物胁迫的反应中使用钙离子作为信号分子和调节剂。我的研究重点是了解植物细胞使用钙离子和钙结合蛋白来调节应激反应和发育的独特方式。我的实验室在我们的研究计划中使用了各种分子，遗传和生物化学工具。这项工作将促进我们对植物细胞生物学和胁迫生理学的认识。这项研究对学术界、生物技术界和农业界都很重要。它为未来旨在工程增强加拿大作物的抗逆性的应用提供了基础。

Plants must continually monitor their environment and respond to changes with appropriate cellular and physiological adaptations. When faced with adverse environmental stress such as pathogen attack, drought, or salinity, plants initiate specific, adaptive cellular responses which include changes in gene expression, enzyme activity, and metabolic adjustments. These responses are regulated through intricate signalling systems that help orchestrate the cell's machinery into a coordinated response that is appropriately timed and specific for the given stress. Plants use calcium ions as signalling molecules and regulators during responses to virtually all types of biotic and abiotic stress. My research focuses on understanding the unique ways in which plants cells use calcium ions and calcium binding proteins to regulate stress response and development. My lab uses a variety of molecular, genetic, and biochemical tools in our research program. This work will advance our knowledge of plant cell biology and stress physiology. This research is important to the academic, biotechnology, and agricultural communites. It provides the foundation for future applications aimed at engineering enhanced stress tolerance in Canadian crops.