Elucidating the functional role of fronto-striatal-hippocampal networks

传统上，大脑的纹状体和海马体系统被认为是独立的。据认为，纹状体系统参与了刺激反应习惯学习和规则之间的转换。特别是，我们的团队和其他人已经证明，当需要启动新的动作时，纹状体的背侧部分被涉及，而当刺激-反应联系需要加强时，纹状体的腹侧部分被请求。海马体将有助于人类的情景记忆和联想记忆。情节记忆被定义为对可以明确陈述的自传性事件的记忆。它负责回忆过去与特定时间和地点联系在一起的个人经历。联想记忆是情景记忆的一种形式，它被定义为学习和记忆不同项目之间关系的能力。

Traditionally, the striatum and the hippocampus systems of the brain were conceived as independent. It was thought that the striatal system was involved in stimulus-response habit learning and shifting between rules. In particular, our group and others have shown that the dorsal part of the striatum is involved when a novel action need to be initiated, while the ventral part of the striatum is solicited when stimulus-response associations need to be reinforced. The hippocampus would contribute to episodic and associative memory in humans. Episodic memory has been defined as the memory of autobiographical events that can be explicitly stated. It is responsible for the recollection of past personal experiences that are linked with a specific time and place. Associative memory is a form of episodic memory which is defined as the ability to learn and remember the relationship between different items.