Development of N,O Chelated Complexes for the Catalytic Synthesis of Amines and Nitrogen Containing Materials

胺官能团被引入到广泛的天然产物中，称为生物碱，并且是大多数合成和天然存在的生物活性化学品和材料的关键组分，例如药物，农用化学品和抗微生物塑料。用于从更容易获得的起始材料（包括烯烃和醇）选择性地和策略性地合成这种胺官能化的小分子和材料的方法是一个深入研究的领域，其中催化方法作为用于提高能量效率和减少废物副产物形成的优选策略而出现。 催化剂为提高制造效率和商业盈利能力提供了最前沿的机会，因为它们有助于在较低的强制条件下发生化学转化，并且它们控制化学反应的结果，而不是消耗本身。因此，催化剂可以重复使用，并且只需要少量。

Amine functionalities are incorporated into a broad range of natural products called alkaloids and are key components of a majority of synthetic and naturally occurring biologically active chemicals and materials, such as pharmaceuticals, agrochemicals and anti-microbial plastics. Methods for selectively and strategically synthesizing such amine functionalized small molecules and materials from more readily available starting materials, including alkenes and alcohols, is an area of intense investigation with catalytic approaches emerging as the preferred strategy for improving energy efficiency and reducing waste by-product formation. Catalysts offer cutting-edge opportunities for advancing manufacturing efficiency and commercial profitability as they help chemical transformations occur with less forcing conditions and they control the outcome of the chemical reaction while not being consumed themselves. Thus, catalysts can be reused repeatedly and are only required in small amounts.