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Cellular Transport Dispersion in Microfluidic Channels

Cellular Transport Dispersion in Microfluidic Channels
微流体通道中的细胞传输分散
批准号:
RGPIN-2015-06541
负责人:
Ma, Hongshen
金额:
$1.82万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
翻译
细胞的力学性质在医学和生物学的广泛领域中是重要的。例如,疟疾是由一种微小的寄生虫引起的,这种寄生虫的生命周期的一部分是在人体红细胞内度过的。感染这种寄生虫的红细胞的变形性或硬度与寄生虫的生长及其对药物的反应有关。因此,细胞变形性的表征可用于测量寄生虫生长和药物活性。类似地,癌细胞的可变形性可以指示它们侵入健康组织的能力,因此可以用于评估疾病的侵袭性并使临床医生能够选择最佳治疗。
英文摘要
The mechanical properties of cells are important in a wide range of areas in medicine and biology. For example, malaria is caused by a microscopic parasite that spends part of its lifecycle inside human red blood cells. The deformability, or stiffness, of red blood cells infected with this parasite is related to the growth of the parasite and its response to drugs. Therefore, characterization of cellular deformability could be used to measure parasite growth and drug activity. Similarly, the deformability of cancer cells may indicate their ability to invade healthy tissue, and therefore may be used to assess the aggressiveness of the disease and enable clinicians to select optimal treatment.
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Microscopy-based cell separation, selective propagation, and selective single cell sequencing
  • 批准号:
    RGPIN-2020-05412
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.84万
  • 财政年份:
    2022
  • 负责人:
    Ma, Hongshen
  • 依托单位:
Image-based cell sorting
  • 批准号:
    571227-2022
  • 项目类别:
    Idea to Innovation
  • 资助金额:
    $1.46万
  • 财政年份:
    2021
  • 负责人:
    Ma, Hongshen
  • 依托单位:
Microscopy-based cell separation, selective propagation, and selective single cell sequencing
  • 批准号:
    RGPIN-2020-05412
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.84万
  • 财政年份:
    2021
  • 负责人:
    Ma, Hongshen
  • 依托单位:
Deformability based Cell Sorting Enabling Quality Control of Stored Red Blood Cells
  • 批准号:
    538818-2019
  • 项目类别:
    Collaborative Health Research Projects
  • 资助金额:
    $15.48万
  • 财政年份:
    2020
  • 负责人:
    Ma, Hongshen
  • 依托单位:
国内基金
海外基金
Toward a general theory of intermittent aeolian and fluvial nonsuspended sediment transport
  • 批准号:
    --
  • 项目类别:
    --
  • 资助金额:
    55万元
  • 批准年份:
    2022
  • 负责人:
    Thomas Pahtz
  • 依托单位:
Intraflagellar Transport运输纤毛蛋白的分子机理
苜蓿根瘤菌(S.meliloti)四碳二羧酸转运系统 (Dicarboxylate transport system, Dct系统)跨膜信号转导机理
  • 批准号:
    30870030
  • 项目类别:
    面上项目
  • 资助金额:
    30.0万元
  • 批准年份:
    2008
  • 负责人:
    文津
  • 依托单位: