Modeling, Signal Processing and the Design of Novel Instruments and Algorithms Applicable to the Respiratory System

利用线性和非线性信号处理和建模技术以及仪器，这项研究计划将调查、设计、开发和评估适用于呼吸系统及其相关疾病，特别是阻塞性睡眠呼吸暂停(OSA)的新技术。OSA目前影响着超过10%的加拿大人，但也被认为有许多未确诊的病例。阻塞性睡眠呼吸暂停综合征缺乏诊断和治疗，给社会造成了巨大的身体和经济负担。这里提出的研究将通过研究分析和解释生物数据，特别是呼吸声音的新方法来解决这一差距，并设计新的医疗技术，这些技术将在OSA的护理点诊断、治疗和监测中具有未来的应用；一些提议的技术还将具有其他一般应用。

Using linear and non-linear signal processing and modeling techniques and instrumentation, this research program will investigate, design, develop and evaluate novel technologies applicable to respiratory system and its associated disorders, in particular obstructive sleep apnea (OSA). OSA currently affects more than 10% of Canadians, but it is also believed that there are many undiagnosed cases. Lack of diagnosis and treatment of OSA impose an immense physical and economic burden on society. The research proposed here will address this gap by investigating new ways to analyze and interpret biological data in particular breathing sounds, and design novel medical technologies that will have future applications in point of care diagnosis, treatment and monitoring of OSA; some of the proposed technologies will also have other general applications.