Evaluating the structure and size of epoxy oligomers and acrylate polymers for use in functional coatings

细菌和其他微生物对最强大的抗生素治疗的耐药性日益增强，这是一个巨大的挑战，威胁着我们治疗常见感染的能力，对我们普通人群的健康可能产生深远的影响。生物杀灭聚合物是一种可加工的塑料材料，具有抗微生物特性，是对抗微生物感染的一种令人兴奋的工具。特别是，含抗微生物剂N-卤胺的聚合物比传统的基于浸出的系统更环保，毒性更低，同时仍然保持对广谱微生物的活性。一家位于温尼伯的材料科学公司，正在开发复合生物杀灭聚合物，这种聚合物既具有很好的抗微生物活性，又具有使它们能够在从食品制备到医疗保健的一系列环境中作为涂层使用的特性。拟议中的研究将集中在调查材料的特性ofbridgence的专有聚合物前体。一个成功的项目成果将开发合成战略，生产改进的材料，将有利于通过解决一个关键的知识差距方面的聚合物结构和组成及其最终性能的涂层材料。

The growing resistance of bacteria and other microbes towards treatment by the most powerful antibiotics is atremendous challenge that threatens our ability to treat common infections, with potentially profound effects onthe health of our general population. Biocidal polymers are processable plastic materials with antimicrobialproperties that represent an exciting tool in the war on microbial infections. In particular, antimicrobialN-halamine-containing polymers are more environmentally friendly and less toxic than traditionalleaching-based systems, while still remaining active against a broad spectrum of microorganisms. Exigence, aWinnipeg-based materials science firm, is developing composite biocidal polymers that exhibit both promisinganti-microbial activity and properties that allow them to be deployed as coatings in a range of settings, fromfood preparation to health care. The proposed research will focus on investigating the materials properties ofExigence's proprietary polymer precursors. A successful project outcome would develop synthetic strategies forproducing improved materials that would benefit Exigence by addressing a key knowledge gap with respect topolymer structure and composition and their ultimate properties as coating materials.