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Ventilated surgical and post-surgical recovery systems for rodent research

Ventilated surgical and post-surgical recovery systems for rodent research
用于啮齿动物研究的通风手术和术后恢复系统
批准号:
RTI-2018-00955
负责人:
Mohajerani, Majid
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
翻译
我们需要新的啮齿动物手术和术后基础设施,以支持我们在莱斯布里奇大学加拿大行为神经科学中心的研究和培训活动。该应用支持获得移动式通气手术解剖台和恢复柜。莱斯布里奇大学(University of Lethbridge)的vivarium即将从目前的多学科研究机构CCBN大楼搬迁到目前正在建设的新科学大楼,该大楼不仅将容纳CCBN,还将容纳所有自然科学学科,计划于2019年夏季开放。目前,我们没有单独的通风系统来协助啮齿动物手术、术后恢复和灌注/组织收集过程。新vivarium的设计和建造方式使手术、术后恢复和灌注/组织收集室只能容纳单独的通风单元,而现有的传统非移动系统无法搬进新建筑。进行外科手术对我们nserc资助的基于啮齿动物的研究至关重要。如果我们不能获得手术系统和相关的恢复柜,我们的研究项目和受训者的工作将会严重中断。除了提案中概述的将实验中心搬到新建建筑的要求外,通风回收柜是实验中心专家的首选,因为它们可以最大限度地减少压力和昼夜节律干扰,并提供对几个环境因素(如温度)的个性化控制,最终将提高我们发现的科学稳健性。这些关键项目的获取是我们nserc资助的核心
英文摘要
We are requesting new rodent surgical and post-surgical infrastructure to support our research and training activities in the Canadian Centre for Behavioural Neuroscience at the University of Lethbridge. The application is to support the acquisition of mobile ventilated surgical and dissection table together with recovery cabinet. The immediate need is prompted by the imminent move of the vivarium at the University of Lethbridge from its current location in the building housing the CCBN, a multidisciplinary research institute, into a new science building currently under construction, that will house not only CCBN but all natural science disciplines, scheduled to be opened summer 2019. At present, we have no individually ventilated systems to assist with rodent surgery, post-surgery recovery and perfusion/tissue collection processes. The new vivarium was designed and has been constructed in such a way that the surgical, post-surgical recovery and perfusion/tissue collection rooms will only accommodate individually ventilated units and the existing traditional non-mobile systems cannot be moved into the new building. Performing surgical procedures are essential to our NSERC-funded rodent-based research. There will be a significant interruption of our research projects along with the work of trainees if we fail to acquire the surgical systems and associated recovery cabinets. Apart from the requirement prompted by the move of the vivarium into a newly constructed building outlined in the proposal, the ventilated recovery cabinets are preferred by vivarium experts as they minimize the stress and circadian rhythm disturbance and provide individualized control over several environmental factors, such as temperature that will ultimately improve the scientific robustness of our discoveries. The acquisition of these critical items is central to our NSERC-funded
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