NSERC Medtronic Industrial Research Chair in Spine Biomechanics / Chaire de recherche industrielle CRSNG Medtronic en biomécanique de la colonne vertébrale

脊柱整形外科领域的生物医学工程和医疗技术(Medtech)行业面临着**越来越多的挑战，既要开发高质量的工程解决方案来治疗脊柱疾病，又要快速**将研究成果落实到用户手中。脊柱是我们身体的一个复杂而核心的组成部分，参与**平衡姿势、运动和保护脊髓。严重的脊柱畸形、创伤和退行性疾病一般采用脊柱内固定手术进行融合治疗。这是一种**广泛的侵入性手术，永久性地限制了脊柱节段的运动，并在融合节段和未融合节段之间以及结构内部施加额外的**压力，特别是在**骨-种植体界面和致密的结构中。尽管生物医学技术在过去的几十年里有了很大的进步，但脊柱手术仍然非常具有侵入性，而技术仍然主要是经验性的**和特定于外科医生的。这是一个工程研究对提高脊柱**生物力学知识至关重要的领域。**该研究计划旨在开发和应用生物力学工程方法，以：1)提高**对三维脊柱生物力学的理解，以探索新的设备、手术后条件，同时**制定器械指南。2)开发经过验证的模拟工具，旨在分析和**改进器械技术和手术策略；3)开发和验证用于*手术计划、术中指导和手术后管理的创新工具。总而言之，主席的**科技成就将是**正在进行的全球竞争的主要资产**，目的是掌握脊柱生物力学和相关技术的先进知识，并开发**全面的工程工具，以满足脊柱矫形医疗技术行业的重要需求，**为加拿大**生物医疗行业、患者和社会带来所有预期经济效益的侵入性更小和最佳的手术。

Biomedical engineering and medical technology (medtech) industry in the field of spine orthopedics faces**increasing challenges to develop high-quality engineering solutions to treat spine pathologies as well as rapidly**implement research findings to the users. The spine is a complex and central component of our body, involved**in posture equilibrium, movements, and protection of the spinal cord. Severe spinal deformities, trauma, and**degenerative conditions are generally treated with spinal instrumentation surgery involving fusion. This is an**extensive and invasive procedure that permanently restricts motion of spinal segments and places additional**stress on the junction between fused and unfused segments and within the construct, especially at the**bone-implant interface and in dense constructs. Despite significant improvements in biomedical technologies**over the last decades, spinal surgeries remain very invasive while techniques continue to be mostly empirical**and surgeon-specific. This is an area where engineering research is crucial to improve knowledge of spine**biomechanics.**The research program aims to develop and apply biomechanical engineering methods to: 1) Improve**understanding of the 3 dimensional spine biomechanics to explore new devices, post-surgical conditions and,**concurrently, develop instrumentation guidelines. 2) Develop validated simulation tools aimed at analyzing and**improving instrumentation technologies and surgical strategies; 3) Develop and validate innovative tools for**surgical planning, intra-operative guidance, and post-op management of spinal pathologies. In summary, the**scientific and technological achievements of the Chair will represent major assets in the global competition**now underway to master advanced knowledge of spine biomechanics and related technologies, and develop**comprehensive engineering tools to address important needs from the spine orthopedic medtech industry,**resulting in less invasive and optimal surgeries with all the expected economic benefits to the Canadian**biomedical industry, patients, and society.