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PINK1 Inhibition as a Novel Therapeutic Strategy to Target Acute Myeloid Leukemia Stem Cells

PINK1 Inhibition as a Novel Therapeutic Strategy to Target Acute Myeloid Leukemia Stem Cells
PINK1 抑制作为针对急性髓系白血病干细胞的新型治疗策略
批准号:
380799
负责人:
Chan Steven M
金额:
$25.36万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2021-03-01

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中文摘要
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英文摘要
Acute myeloid leukemia (AML) is an aggressive type of blood cancer that kills over 1,000 people every year in Canada. Current treatments are often not effective in curing patients because they fail to kill a special type of cells known as leukemia stem ce
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Inhibiting Thrombopoietin Receptor (TPO-R) Signaling as a Novel Approach to Target TET2 Mutation-Driven Clonal Hematopoiesis
  • 批准号:
    489650
  • 项目类别:
    Operating Grants
  • 资助金额:
    $29.82万
  • 财政年份:
    2023
  • 负责人:
    Chan Steven M
  • 依托单位:
Inhibiting Thrombopoietin Receptor (TPO-R) Signaling as a Novel Approach to Target TET2 Mutation-Driven Clonal Hematopoiesis
  • 批准号:
    483332
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Chan Steven M
  • 依托单位:
Role of Thrombopoietin Receptor (TPO-R) Signaling in TET2 Mutation-Driven Clonal Hematopoiesis
  • 批准号:
    472513
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Chan Steven M
  • 依托单位:
Repurposing Metformin to Target TET2 Mutation Driven Clonal Hematopoiesis and Malignant Transformation
  • 批准号:
    434508
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.8万
  • 财政年份:
    2020
  • 负责人:
    Chan Steven M
  • 依托单位:
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