Fouling removal and system optimization of cleaning in place systems

McFlusion Corporation总部位于安大略省的Ancaster，是一家设计、制造和工程服务提供商，为制药和食品加工行业的设备清洁和消毒提供就地清洁（CIP）和就地消毒（SIP）系统。清洗或灭菌是通过CIP或SIP单元的清洗液通过加工生产线中的**组件进行的。McFlusion计划扩大市场，特别是在食品和饮料行业。**扩展到不同的行业和流程将需要使用更短的设计周期时间来定制和优化CIP和SIP系统。为了实现这一目标，McFlusion已经开始与麦克马斯特大学合作，为他们的CIP和SIP系统开发系统分析工具。McFlusion和麦克马斯特大学之间的初步合作的总体目标是：(i)开发一个系统分析工具，可以预测不同生产线的CIP和SIP系统的性能；（ii）检查污垢层的去除率。建议使用OCE和NSERC的资助来**实现这两个目标。将根据现有的相关性、经验数据和分析模型，为典型加工生产线中不同组件的流动和热性能以及污垢去除开发模型。组件的分析模块将与CIP或SIP单元和高级控制器的模型结合到一个系统分析工具中，McFluison可以使用该分析工具来预测不同加工线的CIP单元的性能。

McFlusion Corporation, based in Ancaster Ontario, is a designer, manufacturer and engineering service provider for cleaning in**place (CIP) and sterilization in place (SIP) systems used to clean and sterilize equipment in the pharmaceutical and food**processing industries. Cleaning or sterilization is performed by passing the cleaning fluid from CIP or SIP units through the**components in the processing lines. McFlusion has plans to expand their markets, especially in the food and beverage industries.**Expansion into different industries and processes would require customizing and optimizing the CIP and SIP systems using much**shorter design cycle times. To achieve this, McFlusion has initiated a collaboration with McMaster University to develop system**analysis tools for their CIP and SIP systems. The overall objectives of this initial collaboration between McFlusion and McMaster**University are: (i) To develop a system analysis tool that can predict the performance of CIP and SIP systems for different**processing lines and (ii) To examine the fouling layer removal rates. It is proposed to use funding from OCE and NSERC to**achieve the two objectives. Models will be developed for the flow and thermal performance and fouling removal in the different**components in typical processing lines based on existing correlations, empirical data, and analytical models. The analysis**modules for the components will be incorporated with models for the CIP or SIP units and for the advanced controller into a**systems analysis tool that can be used by McFluison to predict the performance of CIP units for different processing lines.