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Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids

Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids
定义儿童肾病综合征的免疫功能障碍:在不使用糖皮质激素的情况下实现治疗逆转
批准号:
394681
负责人:
Takano Tomoko
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2019-09-01

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中文摘要
翻译
肾病综合征是儿童中最常见的肾脏疾病。受影响的儿童有大量的蛋白质渗漏到尿液中,因此,发展身体肿胀(水肿)。大多数儿童对类固醇治疗有反应,不管其中有多少
英文摘要
Nephrotic syndrome is the most common kidney disease among children. Affected children have massive leakage of protein into the urine and as a consequence, develop body swelling (edema). Most children respond to treatment with steroids, however many of th
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Pathogenesis of idiopathic nephrotic syndrome: defining the role of B cells and autoantibodies reactive to podocyte proteins
Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids
Role of beta-PIX and CdGAP in the pathogenesis of proteinuria
Role of RhoGDIalpha in the pathogenesis of congenital and childhood nephrotic syndrome
  • 批准号:
    266879
  • 项目类别:
    Operating Grants
  • 资助金额:
    $49.07万
  • 财政年份:
    2012
  • 负责人:
    Takano Tomoko
  • 依托单位:
海外基金