Characterization of the SNARE machinery in colonic goblet cells that regulates MUC2 mucin exocytosis in innate immunity
Characterization of the SNARE machinery in colonic goblet cells that regulates MUC2 mucin exocytosis in innate immunity
批准号:
388329
负责人:
Chadee Khrisendath
金额:
$69.38万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2023-09-01
中文摘要
结肠中的粘液双层是宿主防御的第一道防线,其通过形成针对下面的单层上皮细胞的病原体入侵的保护屏障,同时支持健康微生物群以维持体内平衡。对先天性疾病至关重要
英文摘要
The mucus bilayer in the colon is the first line of host defense by forming a protective shield against pathogen invasion of the underlying single layer of epithelial cells while supporting a health microbiota to maintain homeostasis. Critical to innate d
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Colonic mucin biosynthesis, secretion and function in infectious diseases
-
批准号:418754
-
项目类别:Operating Grants
-
资助金额:$72.03万
-
财政年份:2020
-
负责人:Chadee Khrisendath
-
依托单位:
Colonic mucin biosynthesis, secretion and function in infectious diseases
-
批准号:320278
-
项目类别:Operating Grants
-
资助金额:$65.19万
-
财政年份:2015
-
负责人:Chadee Khrisendath
-
依托单位:
Colonic mucin biosynthesis, secretion and function in infectious diseases
-
批准号:222967
-
项目类别:Operating Grants
-
资助金额:$64.17万
-
财政年份:2011
-
负责人:Chadee Khrisendath
-
依托单位:
CRC Tier 1
-
批准号:265725
-
项目类别:
-
资助金额:$101.99万
-
财政年份:2011
-
负责人:Chadee Khrisendath
-
依托单位:
海外基金