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Hemozoin Crystal: A Metabolic Waste Responsible for Inflammatory-Related Pathologies Developed During Malaria Infection.

Hemozoin Crystal: A Metabolic Waste Responsible for Inflammatory-Related Pathologies Developed During Malaria Infection.
疟原虫色素晶体:一种代谢废物,导致疟疾感染期间产生的炎症相关病理。
批准号:
199346
负责人:
Olivier Martin
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2010-09-01

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中文摘要
翻译
过去,我们已经能够清楚地证明原生动物寄生虫利什曼原虫可以影响MO信号导致其功能障碍,从而提供了一个安全的生态位,寄生虫可以在其受感染的宿主内分裂和发展。这些
英文摘要
In the past, we have been able to clearly demonstrate that the protozoan parasite Leishmania can affect the MO signaling leading to its dysfunctions, thus providing a secure niche where the parasite can divide and progress within its infected host. These
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Cellular and Molecular Mechanisms Underlying Leishmania-Macrophage Interaction: Impact on Cutaneous Leishmaniasis Progression.
Hemozoin and Malaria Biomarkers: Role in the modulation of inflammatory responses and development of Malaria-related Pathologies
Hemozoin: An Inorganic Heme-Based Crystal Responsible for Hepatosplenomegaly Development During Malaria.
Subversion of Macrophage Signaling by the Protozoan Parasite Leishmania
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