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Role of microbes in the pathogenesis of PIBD: From discovery, through causation, to novel treatments

Role of microbes in the pathogenesis of PIBD: From discovery, through causation, to novel treatments
微生物在 PIBD 发病机制中的作用:从发现、因果关系到新疗法
批准号:
417360
负责人:
Vallance Bruce A
金额:
$145.7万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
翻译
炎症性肠病(IBD)是一种慢性疾病,会损害一个人的肠道并导致终身疼痛。IBD在加拿大越来越常见,尤其是在儿童中。目前的治疗(药物)抑制患者的免疫系统,不起作用
英文摘要
Inflammatory bowel diseases (IBD) are chronic conditions that damage a person's intestines and cause lifelong pain. IBD is becoming more common in Canada, especially in children. Current treatments (drugs) suppress patient's immune systems and don't work
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会议论文
Colonic mucus-derived sugars fuel the growth and virulence of pathogenic enteric bacteria.
  • 批准号:
    478324
  • 项目类别:
    Operating Grants
  • 资助金额:
    $69.66万
  • 财政年份:
    2023
  • 负责人:
    Vallance Bruce A
  • 依托单位:
Colonic Goblet Cells and Mucus: Defining Their Roles in Host Defense and Mucosal Protection
  • 批准号:
    443607
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.88万
  • 财政年份:
    2021
  • 负责人:
    Vallance Bruce A
  • 依托单位:
Role of microbes in the pathogenesis of PIBD: From discovery, through causation, to novel treatments
  • 批准号:
    399166
  • 项目类别:
    Operating Grants
  • 资助金额:
    $1.82万
  • 财政年份:
    2018
  • 负责人:
    Vallance Bruce A
  • 依托单位:
SIGIRR: Preserving Gut Defense by Suppressing Epithelial TLR/IL-1R Signaling
  • 批准号:
    380169
  • 项目类别:
    Operating Grants
  • 资助金额:
    $72.45万
  • 财政年份:
    2018
  • 负责人:
    Vallance Bruce A
  • 依托单位:
海外基金