课题基金 / 基金详情

Supplementation of folic acid or methyltetrahydrofolate to reduce developmental anomalies in a new mouse model for the MTHFR 677C>T polymorphism

Supplementation of folic acid or methyltetrahydrofolate to reduce developmental anomalies in a new mouse model for the MTHFR 677C>T polymorphism
补充叶酸或甲基四氢叶酸可减少 MTHFR 677C>T 多态性新小鼠模型的发育异常
批准号：
419078
负责人：
Rozen Rima
金额：
$61.58万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-03-01 至 2025-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=419078&lang=en
关键词：
Developmental Anomalies Folate Metabolism Folic Acid Gene-Nutrient Interactions Genetic Polymorphism Methyltetrahydrofolate Mthfr

项目摘要

项目成果

Rozen Rima的其他基金

相似基金

相关文献

中文摘要
翻译
神经管缺陷（NTD）是由于饮食中叶酸不足。通过叶酸（FA）食品强化和食用含FA的维生素，NTD率降低。常见的遗传变化是亚甲基四氢叶酸还原酶的677C>T突变
英文摘要
Neural tube defects (NTD) are due to inadequate dietary folate. NTD rate has decreased via folic acid (FA) food fortification and consumption of FA-containing vitamins. A common genetic change is a 677C>T mutation in methylenetetrahydrofolate reductase
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Adequate intake of choline in pregnancy may be critical for MTHFD1 synthetase deficiency, a common genetic variant in folate metabolism
Methylenetetrahydrofolate reductase (MTHFR) and multifactorial diseases
19.98CIHR Health Professional Student Research Award vouchers.
  • 批准号：
    234961
  • 项目类别：
    Summer Student Programs
  • 资助金额：
    $6.19万
  • 财政年份：
    2012
  • 负责人：
    Rozen Rima
  • 依托单位：
    McGill University
Trifunctional folate-metabolizing enzyme MTHFD1: impact on birth defects and cancer
海外基金