Equipment and Instrumentation for Tissue Culture Assay Development and Implementation

这项提案要求为一套设备和仪器提供资金，以便在现场建造细胞和组织培养设施。细胞培养是所有细胞和分子生物学研究的关键。细胞和组织培养提供了研究细胞的正常和病理生理和生物化学以及检查药物和有毒化合物对细胞和组织的影响的能力。它还用于药物筛选和开发，以及抗体、疫苗和植物克隆等生物化合物的大规模制造。有了设备齐全的组织培养套件，我们希望开发和进行机制研究，确定新的和现有的化学制剂在体外的有效性和毒性参数。该项目的目的是支持应用学习、正在进行的应用研究，并在天然产品、营养食品和药品领域建立和加强行业伙伴合作研究的能力。

This proposal requests funding for a suite of equipment and instrumentation for the purpose of building cell and tissue culture facilities on site. Cell culture is critical to all cellular and molecular biology research. Cell and tissue culture provides the capacity to study normal and pathological physiology and biochemistry of cells as well as to examine the effects of drugs and toxic compounds on cells and tissues. It is also used in drug screening and development, as well as large scale manufacturing of biological compounds such as antibodies, vaccines and plant clones. With a fully equipped tissue culture suite, we expect to develop and conduct mechanistic studies that define parameters of efficacy and toxicity for novel and existing chemical agents in vitro. The purpose of this project is to support applied learning, ongoing applied research, and to build on and enhance the capacity for industry partnered collaborative research in the areas of natural products, nutraceuticals and pharmaceuticals.