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Mechanisms of Allosteric Regulation of M. tuberculosis Proteasome Function

Mechanisms of Allosteric Regulation of M. tuberculosis Proteasome Function
结核分枝杆菌蛋白酶体功能的变构调节机制
批准号:
433624
负责人:
Vahidi Siavash
金额:
$60.75万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01

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中文摘要
翻译
结核病(TB)是由结核分枝杆菌(Mtb)引起的传染性肺部疾病。据世界卫生组织称,结核病是全球单一传染病导致死亡的主要原因。在加拿大,结核病是土著人民中的公共卫生危机
英文摘要
Tuberculosis (TB) is an infectious lung disease caused by Mycobacterium tuberculosis (Mtb). According to the WHO, TB is the leading cause of mortality from a single infectious agent worldwide. In Canada, TB is a public health crisis among Indigenous peopl
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Disrupting the Pathogens' Communication Lines: The Next Frontier in Combating Antimicrobial Resistance
  • 批准号:
    492393
  • 项目类别:
  • 资助金额:
    $0.15万
  • 财政年份:
    2023
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    Vahidi Siavash
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Developing allosteric inhibitors of mitochondrial ClpP protease for acute myeloid leukemia
  • 批准号:
    489309
  • 项目类别:
    Operating Grants
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    $83.32万
  • 财政年份:
    2023
  • 负责人:
    Vahidi Siavash
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Development of boron-based inhibitors of the mitochondrial ClpXP protease to combat AML
  • 批准号:
    472460
  • 项目类别:
    Operating Grants
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    $7.29万
  • 财政年份:
    2022
  • 负责人:
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The Bhagirath Singh Early Career Prize in Infection and Immunity: Mechanisms of Allosteric Regulation of M. tuberculosis Proteasome Function
  • 批准号:
    446144
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.91万
  • 财政年份:
    2020
  • 负责人:
    Vahidi Siavash
  • 依托单位:
海外基金