Rapid development of automated antiviral lighting systems for use as a COVID-19 prevention tool

安全防病毒技术公司(SATI)正在开发新型抗病毒照明系统(AVLS)，该系统利用紫外线(UV)作为强大的抗病毒工具，自动为大型公共场所消毒。AVLS将使商业和机构建筑能够显著减少病毒从经常接触的表面传播，在新冠肺炎大流行和未来疫情期间提供加强的保护。AVLS还将提供标准的“白光”房间照明，使这一独特的照明系统能够很容易地取代现有照明设备中的荧光管和LED。暴露在UV波长下是科学文献中描述的一种病毒消毒策略，可以通过非特异性DNA/RNA损伤的机制实现对多种病毒的快速灭活。SATI正在将紫外线消毒应用于新冠肺炎大流行，开发AVLS作为针对SARS-CoV-2的快速部署的感染控制干预措施。该项目将为AVLS的开发和商业化提供所有抗病毒功效测试，由多伦多斯卡伯勒大学病毒学助理教授克里斯蒂娜·古佐博士监督进行。Guzzo博士的团队将进行测试，以确定最佳抗病毒活性的适当紫外线照射参数，并进行后续的现场测试，以确保在可以部署AVLS的典型商业地点具有持久的抗病毒活性。AVLS包括正在申请专利的技术，并将是市场上第一个包括实时反馈控制的照明系统，其紫外光与所需的房间照明完全集成，使办公室、会议室、公共卫生间、飞机、地铁、公交车和其他高流量区域的安装变得容易，从而将日常互动中的病毒传播降至最低。该项目对于验证AVLS的抗病毒效果和指导商业设计是至关重要的。该项目完成后，可以迅速部署AVLS，以改善职业健康和安全，将加拿大人带回更安全的工作场所，并降低日常接触中病毒传播的可能性。

Safe Antivirus Technologies Inc. (SATI) is developing novel antiviral lighting systems (AVLS) that utilize ultraviolet light (UV) as a powerful antiviral tool to automatically sanitize large public spaces. The AVLS will enable commercial and institutional buildings to significantly reduce the transmission of viruses from commonly touched surfaces, offering enhanced protection during the COVID-19 pandemic and future outbreaks. The AVLS will also supply the standard "white-light" room lighting, enabling this unique lighting system to be readily installed in place of fluorescent tubes and LEDs in existing light fixtures. Exposure to UV wavelengths is a well-described sanitization strategy for viruses in the scientific literature and can achieve rapid inactivation of a broad range of viruses via a mechanism of non-specific DNA/RNA damage. SATI is applying sanitizing UV light to the COVID-19 pandemic by developing the AVLS as a rapidly deployed, infection control intervention against SARS-CoV-2. This project will provide all of the antiviral efficacy testing for the development and commercialization of the AVLS, performed under the supervision of Dr. Christina Guzzo, an Assistant Professor of Virology at the University of Toronto Scarborough. Dr. Guzzo's team will perform tests to delineate the appropriate UV illumination parameters for optimal antiviral activity, and subsequent field testing to ensure durable antiviral activity in representative commercial sites where the AVLS can be deployed. The AVLS includes patent-pending technologies and will be the first lighting system on the market to include real-time feedback controls, with UV light that is fully integrated with required room illumination, enabling ease of installation in offices, boardrooms, public washrooms, airplanes, subways, buses and other high-traffic areas to minimize the spread of viruses in everyday interactions. This project is critically needed to validate antiviral efficacy and guide commercial design of the AVLS. Upon completion of this project the AVLS can be rapidly deployed to improve occupational health and safety, bringing Canadians back to a safer workplace, and decreasing the likelihood of viral transmission in daily encounters.