课题基金 / 基金详情

Development of innovative therapeutic strategies in cystic fibrosis for improvement of CFTR-targeted treatments and restoration of airway epithelial integrity in infected lungs from patients harboring various mutations

Development of innovative therapeutic strategies in cystic fibrosis for improvement of CFTR-targeted treatments and restoration of airway epithelial integrity in infected lungs from patients harboring various mutations
开发囊性纤维化的创新治疗策略，以改善 CFTR 靶向治疗并恢复携带各种突变的患者感染肺部的气道上皮完整性
批准号：
443897
负责人：
Brochiero Emmanuelle
金额：
$61.02万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-04-01 至 2026-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=443897&lang=en
关键词：
Airway Epithelial Repair Bacterial Infections Cftr Cftr Modulators Cystic Fibrosis K+ Channels Lung Damage Patient-Derived Primary Cells And Living Tissues Respiratory Health Therapeutic Strategies

项目摘要

项目成果

Brochiero Emmanuelle的其他基金

相似基金

相关文献

中文摘要
翻译
囊性纤维化（CF）是加拿大最常见的致命遗传疾病，是由一种名为CFTR的蛋白质编码基因突变引起的。虽然CF影响许多器官，但由细菌感染引起的进行性肺损伤仍然是mo的首要原因
英文摘要
Cystic fibrosis (CF), the most common fatal genetic disease in Canada, is due to mutations in the gene coding for a protein called CFTR. Although CF affects many organs, the progressive lung damage due to bacterial infections remains the first cause of mo
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
K+ channels as key targets to favor alveolar epithelial integrity and function during the resolution of acute respiratory distress syndrome
K+ channels as key targets to favor alveolar epithelial integrity and function during the resolution of acute respiratory distress syndrome
Therapeutic strategies for improvement of airway epithelial repair by targeting CFTR defect and bacterial infection in cystic fibrosis patients
Alveolar epithelial integrity after acute lung injury: control of repair mechanisms by K+ channels
海外基金