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Identification of cell adhesion factors implicated in leukemic cell survival

Identification of cell adhesion factors implicated in leukemic cell survival
鉴定与白血病细胞存活相关的细胞粘附因子
批准号:
197110
负责人:
Mercier François
金额:
$13.66万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-10-01 至 2012-10-01

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中文摘要
翻译
大多数血细胞是在长骨的骨髓中产生的,由造血干细胞产生。这些干细胞存在于一个被称为干细胞生态位的支持性环境中。越来越多的证据表明,血液细胞的癌症,如白血病
英文摘要
Most blood cells are made inside the marrow of long bones, arising from blood-forming stem cells. These stem cells reside in a supportive environment called the stem cell niche. There is mounting evidence that cancers of the blood cells, such as leukemias
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Understanding the role of eIF4A in AML progression and relapse
Deciphering the role of the E3 ubiquitin ligase HERC1 in the chemotherapy response of acute myeloid leukemia.
Identification of in vivo regulators of leukemic growth.
Identification of signaling pathways driving leukemic stem cell fitness in murine models of leukemia development
  • 批准号:
    277921
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $13.66万
  • 财政年份:
    2013
  • 负责人:
    Mercier François
  • 依托单位:
海外基金