Investigation of endoplasmic reticulum calcium signaling in striatal neurons of the YAC128 Huntington’s disease mouse model
Investigation of endoplasmic reticulum calcium signaling in striatal neurons of the YAC128 Huntington’s disease mouse model
批准号:
466585
负责人:
Cheng Judy (Li-Hsuan)
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-12-01 至 2022-12-01
中文摘要
亨廷顿病(HD)是一种神经退行性疾病,其特征是运动控制丧失、不自主运动和认知缺陷。HD源于亨廷顿蛋白基因(HTT)的突变,涉及纹状体(a b)内的信号中断
英文摘要
Huntingtons disease (HD) is a neurodegenerative disorder characterized by loss of motor control, involuntary movement and cognitive deficits. HD results from a mutation on the Huntingtin gene (HTT) and involves disrupted signaling within the striatum, a b
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