Dissecting calcium signalling in basal land plants

剖析基础陆地植物中的钙信号传导

• 批准号: 2749880
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2749880
• 关键词: Dissecting; calcium; signalling; basal; land

Plants need to respond to the environment in order to adapt and grow. Plants often modify the concentration of calcium ions in their cells in response to different environmental stimuli and stresses [1]. These changes in cellular calcium concentration trigger many downstream responses, including re-programming of gene expression. Calcium signalling pathways are therefore essential for plants to respond and adapt to environmental stimuli and stresses. Higher plants, such as the model plant Arabidopsis thaliana, have extensive networks of proteins associated with calcium signalling pathways, and traditional genetic studies have identified mutants in components of these pathways. However, genetic redundancy is often observed and this has hindered further study of these signalling pathways. Recent genomic analyses have revealed that the gene families encoding components of calcium signalling pathways are considerably smaller in basal land plant species, e.g. the liverwort Marchantia polymorpha [3]. The study of these pathways in basal land plants will therefore offer unique insights and understandings into calcium signalling pathways in higher plants, and may identify new potential targets that could be manipulated to improve stress tolerance in crop species.

为了适应和生长，植物需要对环境做出反应。植物经常改变细胞内钙离子的浓度以应对不同的环境刺激和胁迫。这些细胞钙浓度的变化引发了许多下游反应，包括基因表达的重新编程。因此，钙信号通路对植物响应和适应环境刺激和胁迫至关重要。高等植物，如模式植物拟南芥，具有广泛的与钙信号通路相关的蛋白质网络，传统的遗传研究已经确定了这些通路成分的突变体。然而，遗传冗余经常被观察到，这阻碍了这些信号通路的进一步研究。最近的基因组分析表明，在陆生植物物种中，编码钙信号通路成分的基因家族要小得多，例如地茅（Marchantia polymorpha）。因此，对基生植物钙信号通路的研究将为高等植物钙信号通路提供独特的见解和理解，并可能确定新的潜在靶点，可以通过操纵来提高作物物种的抗逆性。