New nickel compounds for sustainable catalysis

连接到过渡金属配合物上的配体对其反应性具有深远的影响。配体结构和相应复合物的反应性之间的关系通常不是很清楚，并且有很多机会通过检查新的配体支架来开发新的反应性。该项目将通过应用Drover教授在有机金属合成和配体设计方面的专业知识，以及纳尔逊博士在物理有机化学和计算建模方面的专业知识，深入了解如何使用不同的配体在镍催化领域实现新的反应性和选择性。其目的是通过一系列研究来检查关键步骤，如氧化加成和金属转移，这对广泛使用的反应至关重要。该项目还将利用Drover教授开创的一套刘易斯酸官能化配体。

The ligands that are attached to a transition metal complex have a profound influence on its reactivity. The relationship between ligand structure and the reactivity of the corresponding complex is not often well understood, and there are many opportunities to develop new reactivity by examining new ligand scaffolds. This project will develop a thorough understanding of how different ligands can be used to achieve new reactivity and selectivity in the field of nickel catalysis by applying Professor Drover's expertise in organometallic synthesis and ligand design, and Dr Nelson's expertise in physical (in)organic chemistry and computational modelling. The aim is to do so via a series of studies examining key steps, such as oxidative addition and transmetalation, that are crucial to widely-used reactions. This project will also make use of a set of Lewis acid-functionalised ligands that have been pioneered by Professor Drover.