One Child Every Child: A Transformational Child Health Research Initiative

加拿大和世界各地的儿童面临着不平等、障碍和强加的条件，使他们无法过上最光明和最充实的生活。我们对儿童的失败是明显的，下降趋势令人清醒：2020年，联合国儿童基金会在儿童健康和健康成果方面将加拿大从2007年的第12位降至38个富裕国家中的第30位。这一缺陷在土著儿童中最为明显，殖民主义和系统性种族主义的历史加剧了这一缺陷。加拿大未能优先重视儿童健康方面的战略投资，“每个儿童一个孩子”倡议将是第一个颁布土著和非土著研究和知识动员并行道路的倡议。它共同关注三个主题，这些主题位于最大的需求和发现和影响的机会的交叉点：更好的开端解决孕产妇和围产期健康;精确的健康和健康开发创新的诊断，治疗和有针对性的社会干预措施;易受影响的繁荣解决神经多样性和心理健康的挑战，包括健康的社会决定因素。在每个主题中，跨学科团队解决生物医学，社会，社会，经济和结构性决定因素，以推进重大挑战项目。这种方法将独特地培养未来的健康研究领导者。交叉加速器提供学科专业知识，创新和资源，包括致力于公平，多样性和包容性的加速器。解决办法包括建设土著主导的奖学金能力和尊重土著自决。我们的跨部门知识调动战略将推动转型变革，这项提议是加拿大第一个统一的儿童健康战略研究伙伴关系。我们的伙伴关系增强了我们的变革能力。这些包括我们在阿尔伯塔及以外的学术合作伙伴，省级医疗保健团队，加拿大儿童健康研究机构，以及各种跨部门的网络，包括健康未来网络。我们将共同创造变革性的知识，有效解决健康差距，促进经济增长和社会创新。我们将改变加拿大儿童健康研究的全球影响力，促进土著主导的知识创造和自决，并推动发现和创新。

Children in Canada and across the world face disparities, barriers and impositions that prevent them from living their brightest and fullest lives. Our failings towards children are stark and the downward trend sobering: In 2020, UNICEF ranks Canada 30th among 38 wealthy countries in child health and wellness outcomes, down from 12th in 2007. This failing is most pronounced for Indigenous children, exacerbated by a history of colonialism and systemic racism. Canada has failed to prioritize strategic investments in child health.The One Child Every Child Initiative will be the first to enact Indigenous and non-Indigenous Parallel Paths of research and knowledge mobilization. Jointly it focuses on three themes situated at intersections of greatest need and opportunity for discovery and impact: Better Beginnings addresses maternal and perinatal health; Precision Health and Wellness develops innovative diagnostic, therapeutic and targeted social interventions; Vulnerable to Thriving addresses challenges of neurodiversity and mental health, including social determinants of health. Within each theme, interdisciplinary teams address biomedical, social, societal, economic, and structural determinants to advance grand challenge projects. This approach will uniquely train future health research leaders. Cross-cutting accelerators provide disciplinary expertise, innovation and resources, including an accelerator dedicated to equity, diversity and inclusion. Solutions include building capacity for Indigenous-led scholarship and respect for Indigenous self-determination. Transformational change will be driven by our cross-sectoral knowledge mobilization strategy.This proposal represents Canada's first unified strategic research partnership for child health. Our capacity for transformation is magnified by our partnerships. These include our academic partners in Alberta and beyond, provincial health care teams, the Canadian child health research institutes, and diverse cross-sectoral networks, including the Inspiring Healthy Futures Network. Together we will generate transformative knowledge and effectively address health disparities to foster economic growth and social innovation. We will transform child health research in Canada with global impact, promote Indigenous-led knowledge creation and self-determination, and drive discovery and innovation.